Epilepsy research project - protocol published

PenCRU and the PenCLAHRC Evidence Synthesis Team are leading a project to select a core outcome set for research in rolandic epilepsy. This is called the Core Health Outcomes In Childhood Epilepsy (CHOICE) study. This work is part of programme of research called Changing Agendas on Sleep, Treatment and Learning in Childhood Epilepsy (CASTLE) led by colleagues at King’s College London.

The protocol for the CHOICE study has been published. You can access this protocol for free

A protocol is plan for a specific piece of research. It describes in detail what researchers will do during the research study. Publishing protocols in advance helps to improve the rigorousness, quality and transparency of research. Before being accepted for publication our protocol was scrutinised by peer reviewers and editors and revised accordingly.

Key points:

  • There is no established core outcome set for childhood epilepsy.
  • Aim of work is to select a core outcome set to be used in evaluative research of interventions for children with rolandic epilepsy.
  • First, the research team will identify what outcomes should be measured, and then then decide how to measure those outcomes.
  • We will review which outcomes have been measured in research about rolandic epilepsy.
  • Families, charities and health, education and neuropsychology professionals will be invited to participate in a Delphi survey. In this, participants will rate the importance of outcomes in several rounds. This helps to achieve consensus between families and health professionals on the more important outcomes that should be measured in research.
  • A face-to-face meeting will be convened to ratify the core outcome set.
  • Then research team will then review and recommend ways to measure the shortlisted outcomes using clinical assessment and/or patient-reported outcome measures.

You can find out more about the CHOICE and CASTLE studies on our CASTLE & CHOICE project page

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